who needs UncertaintyManager®?
UncertaintyManager® – rapid determination of measurement uncertainty of analytical results
UncertaintyManager® tells you the sources of uncertainty in your method
Knowledge of the uncertainty is a precondition for correctly assessing the results of any measurement. Whether threshold values have been exceeded or whether a product meets its specifications can only be determined if the uncertainty of the measurement is taken into account. UncertaintyManager® is therefore a very important tool for analytical laboratories working in the following and related areas:
- testing and calibration laboratories which are accredited according to
ISO/EC/EN/DIN 17025 (2005)
EURACHem/CITAG guide (www.measurementuncertainty.org) - food and beverages
- pharma
- forensic chemistry and doping control
- environmental and waste management

input required for UncertaintyManager®
A range of templates, provided by UncertaintyManager®, can be used to define the analytical procedure:
- equation
- manufacturers and types of instruments used for the measurement
- influences of sample preparation steps
- a choice of types of calibration
- several conditions under which the precision is
- determined
- recovery and standardized methods

data required for the calculation
- data from method validation
- data from a typical measurement
- the overall measurement uncertainty for the analytical procedure
- a histogram that shows the amount of individual uncertainty contributions
- a diagram that shows the trend of measurement uncertainty over the whole working range of the analytical procedure
- the distribution of the result calculated with Monte Carlo
- a cause-and-effect diagram which shows all uncertainty influences and their relationships
- 3 different report formats
- time-saving
using UncertaintyManager, the whole evaluation procedure of measurement uncertainty takes only a few minutes. - easy to handle
- functional user guidance through the different steps of the evaluation procedure
- the software offers different templates
- by generating a flow-chart for the analytical procedure, all data needed are assembled from the extensive database of the system (instrumentation, reference substances, sample preparation)
- two independent calculation methods
- simulation using random numbers (Monte Carlo) takes into account correlations between the uncertainty sources. Monte Carlo is the calculation method of the future.
- uncertainty propagation (formal partial derivatives)
- peak overlap
chromatographic peak simulation for estimation of uncertainty caused by overlapped peaks
- UncertaintyManager® is an efficient tool to meet the requirements of ISO/IEC/EN/DIN 17025(2005) concerning measurement uncertainty.
- UncertaintyManager® is fully compliant with the ISO Guide to the Expression of Uncertainty in Measurement (GUM).
- UncertaintyManager® follows the Eurachem/CITAC Guide to Quantifying Uncertainty in Analytical Measurement.
- Pentium 4 with 3.2 GHz or newer
- 1024 MB RAM (2048 MB recommended)
- Windows Vista or Windows XP(SP2)
- Windows 2000(SP4) possible
- 5 - 10 GB available disk space
- resolution of 1280 x 1024 pixels or more
- Internet explorer version 6.0 or newer
- Adobe reader version 5.x or newer

HPLC/LC-MS*, GC/GC-MS*, IC/IC-MS*, Photometry*,
ICP-OES*, ICP-MS*,
titration, basic operations (reference solution, dry mass etc.)
The database will be updated on a regular basis.
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